Molecular chaperones: How J domains turn on Hsp70s

نویسنده

  • William L. Kelley
چکیده

Molecular chaperones of the heat shock protein 70 (Hsp70) variety facilitate protein folding and assembly. They are assisted in this role by their Hsp40 partners, and recent studies have shed new light on how the 'J domains' of these 'cochaperones' activate substrate binding by Hsp70 molecules.

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عنوان ژورنال:
  • Current Biology

دوره 9  شماره 

صفحات  -

تاریخ انتشار 1999